This is just another case, when you will receive “HTTP Error 503. The service is unavailable”.
In my case I have started form this warning:
Log Name: Application
Source: Microsoft-Windows-User Profiles General
Event ID: 1509
Description: Windows cannot copy file ?C:UsersDefaultAppDataLocalMicrosoftExchange Serverv14Configuration5464_100.sqm to location ?C:UsersTEMP.DOMAIN.001AppDataLocalMicrosoftExchange Serverv14Configuration5464_100.sqm. This error may be caused by network problems or insufficient security rights.
DETAIL – Access is denied.
At first sight I ignored this issue (it seems to be an Exchange problem),but when I look into the username,I saw it was a SharePoint related problem. To repair it, you must give to the reported file sufficient rights. You can do this by going to the specified folder, right click on the file and select the properties. On the Security tab click Advanced and Continue on the warning. When the dialog box is open, the only thing you have to do is to check the “Include inheritable permissions from this object’s parent” checkbox. Close all the windows with OK and from the Administrative command prompt type IISReset /noforce.